Detalhe da pesquisa
1.
IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
EMBO J
; 42(21): e114719, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37737566
2.
IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.
Mol Cell
; 75(4): 669-682.e5, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31302002
3.
Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma.
Br J Cancer
; 125(10): 1365-1376, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34588615
4.
Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program.
Acta Neuropathol
; 138(6): 1053-1074, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31428936
5.
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.
Proc Natl Acad Sci U S A
; 113(47): E7535-E7544, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27821766
6.
Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.
Mol Carcinog
; 51(9): 746-53, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22125164
7.
A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors.
Mol Cancer Ther
; 21(7): 1246-1258, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511749
8.
Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer.
Adv Sci (Weinh)
; : e2204211, 2022 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36373729
9.
p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Nat Commun
; 13(1): 2866, 2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35606354
10.
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair.
Oncogene
; 40(31): 5042-5048, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140639
11.
Extramedullary multiple myeloma patient-derived orthotopic xenograft with a highly altered genome: combined molecular and therapeutic studies.
Dis Model Mech
; 14(7)2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33988237
12.
Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor.
Ther Adv Med Oncol
; 12: 1758835920929579, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32670419
13.
PRL-3 overexpression in epithelial cells is induced by surrounding stromal fibroblasts.
Mol Cancer
; 8: 46, 2009 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19586538
14.
The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.
Nat Commun
; 10(1): 3979, 2019 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484926
15.
Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance.
Dis Model Mech
; 11(5)2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666142
16.
Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.
Clin Cancer Res
; 24(15): 3755-3766, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29618620
17.
Absence of MxA induction is related to a poor clinical response to interferon beta treatment in multiple sclerosis patients.
J Neurol
; 263(4): 722-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26872667
18.
MxA mRNA expression as a biomarker of interferon beta response in multiple sclerosis patients.
J Neuroimmunol
; 291: 73-7, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26857498
19.
BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.
Sci Signal
; 8(373): ra38, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25900832
20.
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.
Nat Med
; 21(7): 741-50, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030178